Suicides in Kota, Rajasthan, India

Suicide rate in Kota in Rajasthan, India, is alarming. The government has set up preventive system led by a psychiatrist in Kota. The rate is yet not falling. I don’t think the situation will change unless three things are attended to. I explain the three things.

#1. Fact is that poor parents are selling their land–their only safety net in times of need—to pay the high tuition and expense of their children to succeed in IIT and PMT (medical) entrance exams to get into IIT or prestigious medical colleges. The children there are in continuous fear, apprehension. They are loaded with performance or anticipatory anxiety. They know if they fail then not only they will fail their parent’s dream but will bring financial doom to the family.

Something has to be done to address this issue. Call the parents. Discuss with them. Involve the parents in psychological counseling.

#2. At the end of the day its the child’s brain that will take the exams. The child (students) should speak and teachers should listen, not the other way round. It should be student centered learning, not teacher centered teaching. Teachers should be not teachers but facilitators. I have been schooled in such paradigm. The Dean of the medical school abroad where I was Assoc. Prof. used to open the classroom door and peep in to check if the teacher had started teaching. I was not supposed to teach or the Dean would pull me up for warning. We in that medical school had several techniques to help our students learn. Later on I was picked up by Provost of American University in Bulgaria to be their  Visiting Professor in psychology just because I had right away declared in the first sheet of my cv:  “I don’t teach”.

#3. Nutrition and memory boosting micronutrients and amino acids should be daily provided to these students. The coaching institutes should fund for this. And 7 to 8 hours sleep for every student should be ensured by supervision.

Ratan. (Dr. Ratan Singh, Consultant in Nutritional and Neurobehavioral Psychology).,  91- 141- 4022609,   91 98281 99856


IQ raised: From Moderate Retardation to Normal level.

We in Jaipur Hospital are surprised that with supplements and an anti-epileptic medicine we found child IQ jump from 60 to 100!!!

We will publish it. The child had delayed mile stones, had seizures and was not testable earlier because of his poor attention span that was because of his hyperactivity. He could not do Form Board. Therefore we assessed his development using the Tredgold Developmental Schedule. On this we placed him at developmental quotient 60. And remember he had all mile stones delayed. Overall I had put him in moderate subnormalcy.

Past week, three years down the line, he was brought for follow up, now at his age 11. We again tested him. This time he not only could do the Seguin Form Board but came out as IQ 100.

The ABA was advised on his first visit three years ago, but parents did not go for it. Main intervention was the supplements and sodium valproate prescribed by neurologist for his seizures.

We will document it in detail and publish.

This is the first time we succeeded in raising the IQ. Earlier we tried on another child but failed on the IQ front. But that child was 11 of age when brought to us.

Ratan.,,  91 141 4022609,

+91 9828199856

I am happy, my patient of “schizophrenia” goes to work

I am happy today. A schizophrenic man “recovered” (his word) has gone back to Bombay to work. He works in TV industry. He is an actor. He had stopped psychiatric drugs on his own except one drug. He approached me to stop this psychiatric drug and to stop his remaining symptoms. The remaining symptoms were insomnia and fear that he may be a homosexual and that people in restaurants and the workers there look at him and smile (at him) as if they know he is a homosexual. These were not just ideas of reference but he actually perceived the smiles although when cross checked by his companion his allegation that the restaurant workers smiled was not found valid. I had asked him to take a companion from his family to restaurants to cross check on his idea. When I pointedly asked him if he thought (that the restaurant workers smile at him) or he perceived their smiles, he specifically said he sees them smiling at him, that they know he is a homosexual and this then triggered his fear that he is a homosexual.

He was a hard case but highly motivated to recover. He would call upon me about 10 times daily because of his anxiety. I was very stressed and had blocked his calls. Anyway thankfully that is now history.

What I did is a long story . But few points are as below.

#1. I did not (and never) use any prescription (psychiatric ) medicine.

#2. Of course used vitamins and minerals based on blood tests. Chief among them was niacin.

#3. Used diet manipulations based on home based tests of foods and path lab report.

Details I will report of such cases in formal way in some technical refereed journal.

Ratan,                 ,  91 141 4022609,  +91 98281 99856


Believe It or Not: Psychological Treatment of Chronic Schizophrenia

I know of at least two cases of chronic schizophrenia who got cured—the word is “cured”—with purely psychological procedure. Below is their brief.

Case #1. Young girl having schizophrenia. Late Dr. Ainslie Meares cured him. He was a psychiatrist who toured ashrams in India, Burma and Nepal to learn from Yogis their pain control techniques because he used to get patients with chronic pain. In his book “Relief Without Drugs” he writes that he didn’t get anything particularly useful until he met late Shiva Puri Baba. I cannot write enough on Shiva Puri Baba because there is a full book, The Long Pilgrimage, written by the son in law of cousin of Lord Minto. How can I compress a book in few lines? So I will be brief. But before that imagine a white British (by the way Meares was also white, writing about Shiva Puri Baba) writing a book in praise of a brown “slave” that all of us were at that time of history. The book The Long Pilgrimage is out of print. A Yogini from New York gifted this book to me. This book says there are clues in various places in the Rig Veda that prove that the civilization of that time that existed before the last Ice Age somehow found a way to pass on the knowledge to us.

Please note I am not a Hindu fanatic, nor a BJP lover. But I have to state the facts as I read them.

The out-of-print book describes that Shiva Puri Baba was from Kerala (so was the Adi Shankaracharya). A Brahmin whom his grandfather gave Sanyas Diksha while he was still a child. After Sanyasa he naturally went to jungle and lived there among animals for 25 years. He went on to live until age 140 and the photograph in the book shows his black hair until the end. When he emerged from the jungle in Kerala, he first toured entire India on foot and reached Varanasi where Madan Mohan Malviya ji offered him to be the in charge of BHU. Shiva Puri Baba declined, saying that as a Sanyasi he could not accept any bondage, that he was a free man. All that he had in saving in a small bag of cloth (“Potali”) that was at that time gold and Rupees about 40,000 he gave to Malviya ji, saying that now, only with loincloth as his property, he was truly a free man, a Sanysi. That money was his family property passed on to him. And he went on tour of the world on foot. He went to UK. He was the only non-Muslim who entered the Mecca and Madina sponsored as he was by the original Agha Khan. The queen in UK had given him a fortress to live and passed the order that he could live as long as he wished. She used to meet him daily and maintained a personal diary of the conversations. By the way Shiva Puri Baba spoke excellent English. This diary of the queen was later on destroyed by the secret service after the queen’s death. Shiva Puri Baba went to the Americas (there was no USA) and discovered the Mayan civilization—I mean so is written in that book by the son in law of the cousin of Lord Minto.  When the Baba was in UK fortress there was a caretaker and his son William was a child then. Please remember this William was then a child. Shiva Puri Baba returned to India and settled in Nepal that at that time allowed all saints to live free in Nepal. It was there in Nepal that one day Shiva Puri Baba was walking on road in Nepal and the British Collector was going in his Jeep. This British Collector was none other than William the child whose father was Shiva Puri Baba’s care taker appointed by the British queen. William immediately recognized Shiva Puri Baba who still had hair black. Shiva Puri Baba was given a cottage in jungle and a boy to take care. Eatables were brought to Baba by visitors who used to come for discourses. During discourses a “Chita” used to always come and quietly sit by Baba’s side, listening. There was a special bond between Baba and “Chita”—after all the Baba had lived for 25 years among animals in jungle.

The psychiatrist Dr. Ainslie Meares met Shiva Puri Baba and had long meetings with him for over a week. What “happened” —or not happened, sitting in silence—between the two (more happened in “sitting in silence” than in verbal exchanges) is described by Meares in his book Relief Without Drug and in articles published in Medical Journal of Australia. For example two of Meares’ excellent articles are titled Why Patient Recovers (or it may be What Makes Patients Recover)—not exact words because I am writing extempore although I have all of Meares’ articles and most of his books.

Meares developed a special type of meditation after meeting Shiva Puri Baba plus doing experiments on himself. On his return to Australia Meares wrote letter to the Australian Medical Council stating that he was stopping his medical practice and would practice only meditation on patients. After success with asthma patients he started getting patients of anxiety and physical pain referred by his former medical colleagues. Among them were cancer patients. That is how he got a chronic schizophrenia patient whom he cured solely by his unique technique of meditation. By the way Meares is the only one and his is the only kind of meditation that has shown reversal of confirmed terminal stage cancer of many type and data published in mainstream medical journals.

It took over a year for this girl with schizophrenia to get back to normal track. My comment: When you are cured with nothing (Meares’ meditation was “Doing nothing”—not even doing “Doing nothing”) you don’t relapse.

Case #2. This case is of late Professor John Nash the Nobel laureate. He was forcibly admitted in mental hospital three times. Each time he ran away. I have his two video interviews where he says that he recovered by “cognitive therapy”. He describes this therapy as brain exercises such as found in computer games and chess. By the way now we have scientifically drafted neuropsychological exercises based on Operant Conditioning. Nash’s videos worth watching. Once, after he got the Nobel and the Hollywood movie “A Beautiful Mind” made, a group of psychiatrists in a meeting asked him why he did not complete any course of psychiatric treatment. He stepped back, thought and replied that probably that would make him “Normal” but he would not be creative.

Conclusion: The two cases involve two different procedures, meditation and brain exercises, although both are psychological. For meditation Meares himself has said that his type of meditation involves regression to an evolutionary primitive stage of reptilian brain. Reptiles as you know have pie brain, very small and they lack color vision. Similarly in Meares’ meditation if the meditator opens his eyes slowly, he will not see colors. By the way we all have reptilian brain at the top of medulla oblongata. The limbic brain and the neo-cortex are later additions through evolution. Another mechanism behind his procedure Meares says is lowering of cortisol, cortisol being immuno suppressant (its given to prevent body’s rejection of transplants and also sometimes given to asthmatic patients to suppress immune reaction because asthma is immune system’s over-reaction to something). By the way adrenalin is a marker of transient stress, cortisol is a marker of chronic sustained ever-present stress.

The explanation given for neuropsychological brain exercises is that it changes the brain circuitry. Read it in the context of huge literature on neuro-plasticity.

I must conclude on a realistic note. These above ones are time consuming procedures. In modern times people rather resort to quick fixes even if the fixes give side effects or no effects. But orthomolecular medicine, mostly practiced by naturopathic, holistic medicine praactioners using vitamins, minerals and oils such as omega-3, is increasingly proving effective with or without psychiatric drugs and are found useful to help stop psychiatric drugs without a withdrawal.

Ratan,     ,  91 141 4022609,    +9198281 99856

Immediate Recovery

Immediate-really immediate-Recoveries from Schiz & Depression’

I am preparing an article from my case records on two cases of paranoid schizophrenia whom I brought out of their misery IMMEDIATELY. By “Immediately” I really mean immediately–not hours but minutes!!! I will also give literature citation of similar happening, meaning I am not the first to do it. I am not so lucky with extreme depression as I am with schizophrenia. Here I will report animal research in which rats have had instantaneous recovery from their “Learnt depression”. But if readers can relax on the definition of “Immediate” then I can report one case from my records who recovered from depression in one month. Expanding the area from schizophrenia and depression to other severe conditions such as chronic migraine, I will report recovery in one week from a life long suffering. So hold on. These articles are in progress. So bye for now.

Note: The immediate recovery from schizophrenia in one case and some recovery in another case interrupted by a medicine professor (who believed that vitamins do harm) is reported in another article (uploaded on this web site with the editor’s permission) published in Journal of Orthomolecular Medicine (JOM) under the title “Clinical Responses With Vitamin B3—Report of Two Cases of Schizophrenia”.


Sleep reversal

Sleep Reversal?

Finally I have succeeded in shifting my patient’s sleep pattern from 5 AM through 2 PM (sleep reversal) to the present 12 midnight through 10 AM. Its quite an achievement. I could do it by the following.

#1. Locked the computer room from 10 PM to 6 AM.  But then he started viewing TV overnight..

#2. Changed my focus from his sleeping through the night to keeping him awake through the day. For this I changed the timing of all (except for niacin that he continues to take in morning and evening) B group of vitamins“ including sublingual methyl-cobalamin and omega3 and GLA ( evening primrose oil ) from evening to morning around 8 AM. The care giver would wake him up for the vitamins if he was sleeping. His paranoid ideation was already gone a month ago, mainly due to two heaped teaspoon of niacin morning and evening, equivalent to over 4 gm daily. He used to suspect that people were following him and others could read his thoughts. And all this has been achieved in four months compared to his years of failed psychiatric treatment.  For years he had been on many psychiatric drugs that only gave him sleep, drowsiness and drooling saliva and nothing else. He is now searching for job to earn livelihood.

About a week ago, before my above mentioned interventions, when his paranoid ideas were gone but sleep reversal was continuing, his care giver –to correct his sleep cycle—had re-started the old psychiatric prescription and tried all the five drugs at their full doses that used to put him to sleep for sure. But this time–probably due to the vitamins and omegas–all the psychiatric drugs could not put him to sleep in the night. For five days of full psychiatric drugs trial the “sleep reversal” continued until the idea flashed in me to lock the computer room for nights and keeping him awoke in day.


October 22, 2010: Update on my above mentioned patient.

I had written to the caregiver if we could now take the case as completed to which she replied as follows. Below, as “Update” I have arranged her e-mails date wise as she posted them to me. I also reproduce here e-mails to one NGO with care giver’s prior permission.

On Sept. 23, 2010:

  1. Sir, you have taken us a long long way since the days of last Diwali festival and the approaching one.
  2. We still have a difficult adult on hand but not a depressed zombie.
  3.  I DO NOT think, the job is DONE. ( though there are remarkable improvements)> Ok. We continue.
  4. We still have to observe  his sleep pattern and see what more can be done.> Try to have him take GLA and Mexepa and B vitamins before 8 AM. Our strategy seems to have worked that is to change our focus from having him sleep in the night to having him awoke through the day. And also your reminding me what I did for similar condition in my family helped me recall of GLA and Mexepa.5. What is the next level of treatment for Narendra ( changed name for confidentiality ) that you referred to?> Job for him. And glad to learn that he is also thinking of it and there is hope next week.
  5. My asthma can wait till the time Narendra ( name changed ) becomes a regular taxpayer.
  6. Efforts are going on ( as per the interest shown by Narendra) to set him in a job. Hopefully we will know by the next week.
  7. Getting the job would not be enough in his case but holding it for a few months would be neccessary.
  8. How long is it needed for him to take the mexepa and gla before his sleep pattern normalises?

Sept. 27, 2010:

Sir,The psychotic drugs given to Narendra ( name changed ) for 6 months were Antidep 75 mg, twice a day, Espuzine plus thrice a day, Lozapin 25 twice a day, Veniz XR 37.5, Sulpitac 50 once a day. These drugs ensured his sleep during the 6 months we continued the treatment. After 1 month of Orthomolecular, when he developed sleep reversal which continued for 2 months i again gave him espuzine, lozapin, sulpitac, nepnap for 3 nights. He kept awoke the whole night. After starting on GLA and Mexepa, 2 tab each he has been sleeping at night around 1.10 AM and gets up at 10.30 AM. I read Orthomolecular also worked well for Angina (the heart condition). Narendra”s mother has developed angina due to excessive worry.


Oct. 06, 2010:Sir,

  1. Does Celin ( a sugar free ascorbic acid by Glaxo here in India ) help bowel movements?
  2. Last 25 days, Narendra has been sleeping at night (12.30 AM to 8.30 PM) and is regularly taking gla, maxepa and niacin.
  3. Last few days i have been able to push celin into him, mixed in sugar free juice. Yesterday he reported better bowel movements. I hope celin is the cause and it continues.
  4. Still trying to get him in a job, seems it will take some time.


Date: Tue, 19 Oct 2010 10:01:20 +0530 Subject: Fwd: Ratan, JaipurFrom: [The caregiver]To: ratanpsych@hotmail.comCC:

Sir,1. Narendra ( name changed ) is well, not depressed, no sleep reversal.2. His job has not yet worked out but we are trying.3. His current problem is of very little bowel movement. Initially after Celin he had proper bowel movement but that was only for a day. Since then his B.M is very little and as a result his stomach is protruding and he does not feel light and fresh.4. I think we need to go in for the candida fungus treatment.5. Will candida fungus treatment solve his bowel problems?6. Can you please tell me the process and requirements for the treatment of Candida fungus.regards,[Caregiver]

MY (Ratan Singh’s) CLOSING NOTE: I stop updating now. If anyone wants to know further developments then write to me. If anyone wants to communicate with the caregiver then it has to be through me to protect the caregiver”s privacy.’,

About me and orthomolecular (vitamins, diets) treatment of mental illness

I invite you who are struggling with mental health/illness issues and your caregivers to share the problems. Here I am all ears to your problems. If your questions are brief, then I will answer them. Psychiatrically labeled already? Never mind. Just forget the label. They are without basis and serve no purpose. They are loose groupings of symptoms that generally go together.Psychiatry as you know is not based on cause of illness. So why be hurt by the labels. Just ignore the labels.We however will go by cause/s. You will find that the causes being nutritional, don’t carry a stigma. Obviously our approach is more scientific, rational and effective. .I can compare the rates of recovery in psychiatry as against the rates obtained in caring homes started by missionaries and orthomolecular nutritional approaches. I can also quote an officially report of a province in Canada whereby the government asked the psychiatrists the straight question on cost vis-à-vis effectiveness in a single year. But why waste time? Let us go straight to the point of what we can do nutritionally to help us recover our mental health. Nutrition? Or Psychiatric drugs? Psychiatric drugs are not food. And our body alone, given the nutrients and supplements, can make the right molecules that will surround our brain cells to nourish and keep them in optimal health. How can drugs do that? I can’t understand.As an example, take the selective serotonin reuptake inhibitors (SSRIs). They block the re-uptake or absorption of serotonin. They don’t make more serotonin. Only our body can do that with the right nutrition. If your digestion is good, if you are taking that specific amino acid (a protein) called “tryptophan“ and certain vitamins then our body will make serotonin in plenty. There is a world of difference between “blocking” and “making”. The former, being un-natural, does structural change to our brain. I am here:

I am Dr. Ratan Singh. I work with a mix of orthomolecular therapy, neutralization, hypnosis and meditation as and when suitable for the patient/client. Actually I educate the patient or the caregiver in these and empower them to help themselves.


Certificate in Food & Nutrition; Diploma in Nutrition & Health Education (IGNOU), M. A. (Psychology, AMU), DM&SP (CIP,Ranchi), Ph.D., phones: 91 141 4022609, 91 141 2652561, mobile: +9198281 99856;,,
Consultant in Nutritional & Neuro-behavioral Psychology, Jaipur Hospital, India. Member, International Society of Orthomolecular Medicine Life Member, Nutritional Society of India. Clinical Internship in the Practice of Behavior Therapy (Late Prof. J. Wolpe’s Unit at Temple Univ. Medical School & EPPI, Philadelphia, USA, 1973-75). Author of Nutrition & Supplements in Major Mental Illnesses.

Working experience:

since 1968 in Rajasthan state government mental hospital and later in Bikaner general hospital psychiatry department (1969- 1971),

Lecturer in psychology department in University of Rajasthan (1971- 1973),

Intern in Behavior Therapy with late Prof. Joseph Wolpe, MD, Temple University Medical School & EPPI in Philadelphia, USA (1973 to 1975),

Lecturer and later Reader (Assoc Professor) in psychiatry department of Institute of Medical Sciences, Banaras Hindu University (1975 to 1986)

Assoc. Professor in psychiatry department in University of Science Malaysia Medical School and Hospital (1986 to 1997),

I am now Consultant in Nutritional & Neurobehavioral Psychology, Jaipur Hospital, Near Stadium, Jaipur, India.

I practise orthomolecular therapy (OT) for mental, emotional, behavioral, memory problems and illnesses. I combine OT with behavior therapy. I take children, adolescents, couples, families. I also train families with Autistic/ADHD (Pervasive Developmental Disorders) children in “ABA” and biomedical therapy. I also take up cases of schizophrenia, bipolar, depression, anxiety, anger for OT and nutritional interventions.

Basically I educate the patients and/or caregiver to help themselves.

Please note I am not a physician.

Clinical Responses with Vitamin B3: Report of Two Cases of Schizophrenia

Ratan Singh, Ph.D1
1 Consultant in Nutritional and Clinical Psychology, Jaipur Hospital, India. Email:

Abstract Two cases of schizophrenia are reported. In case #1, the patient quickly stabilized after taking large
doses of niacin. As a result of side effects, the patient discontinued niacin and rapidly regressed. When this
patient resumed niacin for approximately 1 year, he normalized and did not require the vitamin any longer.
In case #2, the patient stabilized quickly from large doses of niacinamide, but discontinued due to vomiting.
“is patient became fearful of niacinamide’s side effects and went on antipsychotic medication, but unfortunately
his level of functionality declined. Both cases highlight the rapidity of therapeutic responses that are
possible when niacin or niacinamide are given to atypical antipsychotic-naïve schizophrenic patients. Given
the track record and low cost of vitamin B3 vitamin supplementation, having few worrisome side effects and
good recovery rates, there is an urgent need to promote orthomolecular medicine in India.

The idea that high doses of niacin or niacinamide could act quickly to stabilize
schizophrenic patients occurred to me upon
reading Hoffer’s interview in which he described
immediate amelioration of auditory
hallucinations in a female schizophrenic
patient that consumed 60 grams (g) of
niacin in one day.1 Here, I report on two
schizophrenic cases. !e patient in Case
#1 consulted me once, and then moved to
another city over 1,000 kilometres away.
In this case, the patient took high doses of
niacin himself, and much like the case that
Hoffer reported, had a favourable therapeutic
!e patient in Case #2 consulted me
for a few days and also moved to another
city. Even though this patient experienced
some notable and fairly immediate improvements
from niacinamide, his outcome
was poor since he discontinued the
vitamin and went on antipsychotic medication

Case #1
J, male, 18 years of age, consulted with
me in the hospital. His father accompanied
him since J was unmanageable, violent, and
aggressive. J was paranoid, believing that his
mother was purposely disrupting his plan to
pass the Indian Institute of Technology (IIT)
entrance exam. He had broken a window, cut
his wrist with a broken piece of glass, and
had written a letter in his blood in which he
described murdering his mother because she
sent him running errands which was distracting
him from his studies. According to
J’s father, he was not really studying. J would
just make plans, buy books, and photocopy
several pages to be read later which he would
never do. He could hardly sit at his desk to
study. At night, he would try to study but
dozed off intermittently. J was living with his
father in a city thousands of kilometres from
his mother, in order to get away from her alleged
disruptions. J needed to move back to
where his mother lived since he was to appear
in class 12 exams in that city. Although his father had promised to keep him in a hotel
and away from his mother, J didn’t believe
his father.
I advised J to take 1 g of niacin, three
times daily. I also added that it would give
him a cutaneous flush, which is a good sign
of blood flowing to the remote areas of the
brain, and that it would increase his focus
and sharpen his mind. J liked it and cooperated—
rather over-cooperated—because he
wished to increase his brain power to pass
the IIT entrance exam. His father purchased
100 g of niacin to test over time, and intended
to buy more if J’s response was good.
Upon reaching the city where his mother
lived, J was given his first dose, 1 g of niacin.
!e next morning, the dose was increased to
5 g, and another 5 g was given in the late evening
because the expected cutaneous flush
did not happen. In the morning of the third
day, J packed his bag, took the niacin bottle,
and barged out of the house without a word
to anyone. His parents became extremely
worried. In a panic, J’s father made a long
distance call to me. I was also worried given
J’s history of paranoia and aggression. !erefore,
I advised J’s father to report the matter
to police and take his son to a psychiatrist
when he was found. All of us were relieved
when J on his own called his father in the
evening and explained that he was staying in
the hotel just opposite his mother’s house. J’s
father asked if he was taking niacin, and if he
had experienced the cutaneous flush. J denied
having had any cutaneous flush. !at night,
desperate to pass the IIT entrance exam, J
took 8 g of niacin as single dose. He had a
deep uninterrupted sleep of eight hours that
night. !e next morning, J’s father went to
the hotel. J was much better. He was obedient,
calm, went home to his mother, and
then greeted her in the typical Indian style.
J requested that she provide some drink and
breakfast, and even asked for permission to
watch television. He watched television for
four hours, and studied as well.
Unfortunately, J was unable to remain
on his current dose of niacin (8 g twice daily)
since he developed severe problems in his
eyes. He reported that his eyes were burning burning,
that white fluid was oozing out, and that
he could not open them. Fearing that niacin
would turn him blind, J and his family
decided to stop niacin. His father called me,
and I advised him to take his son to an ophthalmologist.
His eyes had started recovering
when niacin was discontinued, and they
didn’t need to see any doctor. (Editor’s note:
Niacin has never been shown to cause blindness.
Infrequently, niacin can cause blurred
vision due to cystoid macular edema, which
is completely reversible when the vitamin is
Shortly thereafter, his father called me
and complained that J was relapsing, gradually
getting aggressive, and unmanageable
again. Once again, J fled his home to live in a
hotel. !e next day the hotel manager called
J’s father and complained that J was opening
his shirt, disturbing the hotel guests, and going
to the rooftop. He would also walk until
late in the night without any shirt or trouser.
!e hotel manager requested that J’s father
get his son, or the hotel staff would forcibly
throw him out.
J’s father called me, and asked if he could
restart his son on niacin mixed in yogurt
because J refused to take niacin for fear of
going blind. Because J liked yogurt, his father
opted to hide the niacin in it. At this
point J was not eating and was aggressive
and stubbornly negative. So, I encouraged
the mixing of niacin and yogurt, but added
that this time J’s father should give measured
amounts of niacin, increasing it slowly from
1g three times daily until a cutaneous flush
happens, and then to remain on that dose for
several days before consulting me about the
next steps. J used 100 g of niacin over the
course of a year and stopped since he became
normal. J was now taking private coaching to
prepare for the IIT entrance exam, and was
also getting a helping hand from a student at
IIT. J was a changed person, calmly adjusting
with his mother and studying for the exam.

Case #2
V, a recently graduated medical doctor,
was accompanied by his caregiver when he
consulted me in early April 2010. V and his caregiver were living away from home, preparing
for examinations with the hope of
further study and training overseas. Apparently,
V became aloof, too serious, reticent,
and stopped eating and taking care of his
hygiene. He also reported to his caregiver
that some people were following him, were
tinkering with his motorbike, or that some
people had secretly planted microphones inside
his helmet to keep track of their conversations.
His sleep was disturbed such that
his sleep-wake cycle was reversed. When V
tried to sleep in the night, he would wake
up at 2 AM, and was then unable to sleep
I observed that V’s gait was wobbly and
unstable. I gave him 125 mg niacinamide (I
didn’t have niacin in stock that day) in juice
and waited for 10 minutes to see if there was
nausea and vomiting. When no nausea occurred,
I gave him 1 g niacinamide in juice.
In 5-10 minutes there was a visible change.
His posture softened in the sofa and V gave
a relaxed smile. His gloomy face, poor eye
contact, and difficulty conversing had vanished.
I provided instructions to the caregiver
and both of them left to find a hotel since
they had come from another city to consult
with me. His caregiver said he was seeing a
smile on V’s face for the first time in weeks.
I requested that the dose of niacinamide be
slowly increased to the point of nausea. My
aim was to settle on a dose just below the
nausea-inducing amount. !at night, V took
his meal and slept peacefully. Seeing an improvement,
the caregiver provided 2 g of niacinamide
the next morning. Unfortunately,
V vomited and I instructed him to temporarily
stop the niacinamide. It was stopped
for a day pending the results of liver function
tests. !e enzymes were raised, double their
normal values. V regressed to being gloomy,
shut-in, aloof, not willing to talk, and confined
to bed due to feeling weak. His sleep
became disturbed again and he tossed the
whole night.
As a result of V’s destabilization, I restarted
the niacinamide and some other vitamins.
V was instructed to take 500 mg of niacinamide
in morning and afternoon, and 1 g at night with some juice. He vomited once,
and then developed a mild fever and diarrhoea.
!ese physical symptoms were easily
controlled in two days with an oral isotonic
rehydration drink and probiotics. !e following
day V stabilized on 1 g niacinamide
three times daily in capsules. Capsules were
used instead of tablets since juice was unable
to hide the bitter taste of niacinamide
tablets. V stabilized on 1 g 3 times daily of
niacinamide and traveled to another city to
prepare for his exams.
On April 30, 2010, V’s caregiver sent
me an email. “After today morning’s episode
(where he did not take any other medications
other than niacinamide due to intense sleep)
V has asked me to just bring all the medication
(that is, vitamins) to him and he would
decide the serial order of taking them. We
tried this in the late afternoon and he took
all his medicines on his own. I encouraged
him for that. !is means very soon he will be
observing his regimen on his own. I am very
happy for him about it. He described that
he is for the first time experiencing his body
properly and is getting a general feeling of
and associated weakness. He has stayed
awake for the longest time in the last seven
days today (about hours hours at a stretch
and about six hours in all by now).”
At this stage, I also prescribed 5-hydroxytryptophan
(5-HTP) for V’s sleep
problems, but he vomited. I am uncertain
if the vomiting was due to the 5-HTP or
niacinamide, or both. As a result of the
vomiting, V and his caregiver panicked and
stopped all the vitamins and 5-HTP. !e
two of them were now fearful of the consequences
of vomiting, and started intravenous
rehydration fluid. V’s caregiver reported:
“Presently V is reporting some fear
and suspicion but he is not getting excited
due to that. He is just reporting that those
(paranoid) thoughts are coming more easily
in his mind than before.”
Since V and his caregiver were afraid,
they traveled back to V’s parental home.
When they reached home, they were warned
that vitamins cause central nervous sys-tem toxicity by a family friend, a professor
of medicine. V was promptly referred to a
psychiatrist and subsequently prescribed
antipsychotic medication. In an email correspondence
from his caregiver, V apparently
developed extra-pyramidal symptoms, gait
difficulties, and has gradually worsened since
stopping the niacinamide and 5-HTP. V also
had a return of psychotic symptoms that were
much worse than when he first presented to
my office. His caregiver reported increased
symptoms of schizophrenia, including paranoid
ideation (i.e., being monitored by some
agency all the time), self-talking, being more
guarded, agitation, singing to himself, confining
himself to his room, poor hygiene, and
having no insight into his condition.
In case #1, the pre-niacin baseline stage
when J first came to me, can be labelled as
“A.” !e “B” stage was when J had an immediate
recovery after his deep and uninterrupted
sleep following the high-dose niacin
consumption. !is was followed by another
“A” stage since J regressed from stopping the
niacin because of eye problems. !us, in a
way J’s case followed an ABA design.2 It was
these events that enabled J’s father to clearly
observe that niacin, and not some other factor,
had helped his son.
Why did J not require niacin after the
100 g was consumed? !is was likely a case
of early psychosis and was therefore more
treatable with niacin since the patient was
not on prior psychiatric medication, nor did
the patient have a long protracted course
of mental illness. J might have had a niacin
deficiency, and not a dependency, and therefore
would not necessarily require niacin for
the remainder of his life. J was also receiving
quality psychosocial support from his
parents, and later on from a student already
attending the IIT. !e effectiveness of psychosocial
support in mental illness cannot be
understated. Hoffer described the outcomes
by the Quakers’ psychosocial treatments over
150 years ago with a reported 50 percent recovery
rate – far better than the present day
recovery rates from psychiatric medications.3 Clearly, with the disruptive behaviours gone,
J’s pleasant adaptive behaviours emerged,
which were being sustained by positive psychosocial
influences in his environment.
Moreover, J was now eating regular meals,
such that, whatever little amounts of niacin
he might be getting in foods was sufficient
for him.
In Case #2, I had no follow-up with
V or his caregiver since May 2010, but did
hear about V some 11 months later from a
mutual acquaintance. She informed me that
V was having side effects caused by the antipsychotic
medication given to him and
was still not well. !us, the outcome was not
satisfactory in this case for obvious reasons.
Unfortunately, V was unable to continue the
niacinamide and 5-HTP due to vomiting.
V’s case highlights the potential benefits
from niacinamide, and how atypical antipsychotic
medication can sometimes make
patients worse and less functional than they
were prior to medication.
Both cases highlight the rapidity of therapeutic
responses that are possible when niacin
or niacinamide are given to atypical antipsychotic-
naïve schizophrenic patients. Hoffer reported
that vitamin B3 is more effective when
administered to patients not on atypical antipsychotic
medications since this class of medication
prevents vitamin B3’s therapeutic effects.
4 Hoffer also reported quicker therapeutic
responses to vitamin B3 when it is given early
in a patient’s course of schizophrenia.5 Both
patients were not on any atypical antipsychotic
medication when they were under my care, and
both patients presented early in the course of
their mental illness.
I certainly don’t intend to imply that all
cases of schizophrenia will respond quickly
to niacin or niacinamide as these patients
did. I have had other cases of paranoid
schizophrenia, for example, that responded
within 2 weeks to a gluten free diet. !ere
are many additional orthomolecular treatments
of value if needed.6,7
In a continent like India where the
majority of individuals would be unable to
afford and/or access standard psychiatric
care, orthomolecular medicine is very much needed and it is not cost-prohibitive. India’s
population is 1.119 billion, next to China
with population of 1.337 billion.8 In India,
an estimated 22% of individuals will develop
one or more mental or behavioural disorders
in their lifetime.9 !ere are approximately
3.5 psychiatrists for every one million persons
in India.10 Nearly all psychiatrists are
based in the cities, yet 75% of the population
live in villages and have little-to-no
access to standard psychiatric medical care.
Psychiatrists in India use the full range of
psychotropic drugs with their typical side
effects. Complementary and alternative
medical providers, such as naturopathic
practitioners, Ayurvedic and homoeopathic
physicians, and nutritionists are seldom
aware of the possibility of treating the
mentally ill with orthomolecular medicine,
and their focus is on general practice. !e
non-governmental organizations working
for the mentally ill in India focus on
psychosocial support, and employ the services
of psychiatrists when needed. In the
majority of cases, the preferred method of
treatment is faith healing.11 Even exorcism
is used as a treatment on mental health patients.
12 !ere are less than a handful of orthomolecular
practitioners in India: two are
clinical psychologists (including me), and
one is a psychiatrist who focuses his clinical
practice on pervasive developmental disorders.
Given the track record, easy access
to vitamin supplementation, affordability,
safety, and good recovery rates afforded by
orthomolecular medicine, especially when
combined with adequate psychosocial supports,
there is an urgent need to promote
this therapy in India.
Statement of Informed Consent
Verbal consent was provided for publication
of case #1. Consent was not obtained
for publication of case #2 since the author
lost contact with the patient and his caregiver.
!e editor provides his assurance that all
identifying characteristics have been altered
to protect patient anonymity, but, while doing
so, care has been taken not to affect the
technical aspects of this article.

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7. Pataracchia RJ: Orthomolecular treatment for
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